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Cells, Genes, & Protein Machines
A WebQuest for 5th Grade Science
Introduction
You are a medical intern who has a patient that has come
to you not feeling well. Based on the patient's symptoms, you will
make a diagnosis of the patient's disease. Once you have diagnosed
and researched the disease, you will then report your findings to your
fellow colleagues at the Genetic Disease
Conference for medical interns.
At the conference you will
learn about a wide variety of genetic diseases and disorders. You
will gain an understanding that:
- mutations can affect the function of
an organism
- can result in diseases
- how those diseases are inherited
You will hopefully develop a compassion for people with diseases.
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Task
1. As a medical intern, you have a patient in
your clinic who is ill. Based on the case study with the
symptoms provided to you by the Chief Resident, your job as a medical
intern is to learn what you can about these symptoms and diagnose
this disease.
2. Once you have diagnosed the disease that
this patient has, you will investigate the genetic
disease or disorder and record your findings. You will need to
record the information that you found regarding this disease in your
scientific
journal-pg 1 and
scientific journal-pg 2.
3. You will then create a presentation using
note cards to present the facts you learned in Steps 1 and 2 to
your fellow colleagues at a medical conference, as doctors often
do to share medical information.
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Process
1. First you will be given a case study
prepared by your Chief Resident on a patient who is ill in your clinic.
Each intern (you and your classmates) will receive a different case
study.
2. Each intern will read and review their case
study carefully for clues based the patient description and symptoms.
Based on the information provided on the case study, visit the following
site in order to explore the various genetic diseases and their symptoms.
This will help you to make your diagnosis.
Make Your Diagnosis
Glossary1 Glossary
2 for clarification of terms
3. Important: Once you have diagnosed what you believe
the disease to be, please consult and confirm your diagnosis with
your Chief Resident before proceeding further.
4. Once the disease confirmation has been made,
you may start researching that particular genetic
disease.
5. Please record your research in
your
scientific journal-pg 1
and
scientific
journal-pg 2
as
a way to guide and organize your research. Your Chief
Resident will
provide a copy for you. For your research,
you will need to identify the:
- symptoms
- incidence (who and how
many people get it)
- causes
- how it affects the
person (expected quality of life or what life is
like for the person)
- tests and screening
- how it is inherited
- how it is treated
- would you recommend
testing of parents or siblings and why
6. In order for you to conduct your research, you
will go to the same site that you used to make your diagnosis:
Research Genetic Diseases Here
7. Remember to always cite your sources that were
used for your research and presentation. Use the following
examples to cite your source:
Citation Examples:
Webpage Citation: Last Name, First Name Middle Name.
"Specific Page or Article Title." Title of Entire Web Site. Date
Web Page Was Last Revised. Sponsoring Organization. Date You Read
It <URL>.
8. Once you have investigated your genetic disease,
you will transfer your information neatly to note cards so that you can present to your fellow medical interns at the Genetic Disease Conference.
This will be an opportunity for you to practice your presentation skills
based on the results of your research.
Professionals often meet at conferences in order to present and share
ideas and discoveries with their colleagues.
Note Card Guidelines:
You should have one note card for each aspect
of the disease:
- diagnosis (name of the disease the patient
has) and symptoms
- incidence (who and how many people get it)
- causes
- how it affects the person (expected
quality of life or what life is like for the person)
- tests and screenings available
- how it is inherited
- how it is treated
- would you recommend testing of parents or
siblings and why
9. Some other questions to think about:
How would you
explain to the parents or patient with this disease the following
questions?
- What would you recommend to the family of the patient
based on what you have learned?
- How would you explain to the family how
the disease is inherited?
- Once you have learned what it is like living with the
disease, do you have any ideas on how to make life easier for this
patient?
Remember, as medical interns, it is important to use
compassionate and caring attitudes in relaying information to the family
and patient.
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Evaluation
Rubric
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Conclusion
What an amazing group of medical interns you
are! You have successfully diagnosed, researched, and
presented your findings to your colleagues. You have learned a great
amount of information about other genetic diseases, as well as using
research skills, and collaborating and sharing of information. You
have developed a sense of compassion for your patients by learning about
what life is like for each patient and the difficulties they must deal with
everyday.
Maybe one of you will find a cure for one of these genetic diseases
one day!
If you would like to learn more, you might want to
check out the following links:
Kids Genetics at GlaxoSmithKline: Information on DNA, genes,
heredity, and genetic diseases
Genetics Kids Style: ThinkQuest site with information on DNA,
chromosomes, online quizzes, games, and glossary
For more fun, try these
crossword puzzle
cryptogram
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Teacher Resources
1.
Kerrigan,
Donna. Cells, Genes, & Protein Machines Coloring Book: A Science
Story for Young Readers. Illustrator: Susan Spangler. U.S.
Department of Health and Human Services, Public Health Service, National
Institutes of Health. National Cancer Institute. NIH Publication No.
02-5054. March 2002.
o
To Order, go
to:
https://cissecure.nci.nih.gov/ncipubs/ And select “genetics.”
Select the 2nd
publication title “Cells, Genes, & Protein Machines Coloring Book”
Please note: There
is a limit of 20 copies that can be ordered for free per month. For
phone orders, please call 1-800-4-CANCER (1-800-4226-237).
o
Cells,
Genes, & Protein Machines: A Life Science Story for Young Readers.
U.S. Department of Health and Human Services, Public Health Service,
National Institutes of Health. National Cancer Institute. CD-ROM.
(Copies are currently unavailable from NIH)
2.
The Gene
Scene by
the American Museum of Natural History. Magazine format for students to
understand genetics. The Gene Scene online version
http://www.amnh.org/ology/genetics/
o
To Order
print magazine, go to order form at
http://www.amnh.org/education/resources/card_frame.php?rid=495&rurlid=291
3.
Ology,
the American Museum of Natural History’s website for kids ages 7-12
http://www.amnh.org/ology/
4.
Educator
Genetic Resources from AMNH
http://www.amnh.org/education/resources/rfl.php?set=b&topic_id=3&subtopic_id=43
5.
Kids Genetics
from GlaxoSmithKline
http://www.genetics.gsk.com/kids/index_kids.htm
6.
DNA Detective
from TryScience
http://www.tryscience.org/experiments/experiments_dna_online.html
7.
A Tree of
Genetic Traits
http://learn.genetics.utah.edu/units/basics/print-and-go/traitstree.pdf
8.
American
Museum of Natural History’s Genetic Books List
http://www.amnh.org/education/resources/card_frame.php?rid=693&rurlid=589
9.
Punnett Square from
www.NASAexplores.com
10.
Bardoe,
Cheryl. Gregor Mendel: The Friar Who Grew Peas.
New
York: Abrams Book for Young Readers, 2006.
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Credits
Websites
Dolan DNA Learning Center. "Your Genes, Your Health: A Multimedia
Guide to Genetic Disorders." 2002. Cold Spring Harbor Laboratory.
Internet. 1 October 2004. Available URL: www.yourgenesyourhealth.org
Images
AAA-Backgrounds. "Backgrounds." 2000. Internet.
2 October 2004. Available URL: http://www.aaa-backgrounds.com
Black, Shaun D. "Dr. Black's Medical & Science
Library." Internet. 2 January 2008. Available URL:
http://psyche.uthct.edu/ous/gif/medicons.html
Meisner, Gary. "Phi: The Golden Number: DNA."
2004. Internet. 23 September 2004. Available
URL: http://www.goldennumber.net/dna.htm.
Used with permission.
U.S. Department of Energy Office of Science. "Human
Genome Project Information: Image Gallery." 11 March 2004.
Internet. 23 September 2004. Available URL: http://www.ornl.gov/sci/techresources/Human_Genome/education/images.shtml
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Created by Pamela Aban -- September
27, 2004;
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